CODEINE SULFATE vs IMODIUM A-D

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Attribute	CODEINE SULFATE	IMODIUM A-D
Rating	72/100	70/100
Pharmacy pays	~$20.44 /30	$0.05 /mL
Type	RX	OTC
Active ingredient	CODEINE SULFATE	LOPERAMIDE HYDROCHLORIDE
Manufacturer	Hikma	Kenvue Brands
Dosage forms	Tablet	Capsule, Solution, Tablet
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	None
Half-life	—	about 10.8 hours (range 9.1 to 14.4 hours)
Treats	Cough, Pain	Functional Colonic Diseases, Diarrhea, Bacillary Dysentery

codeine sulfate imodium a-d

Rating

72/100

70/100

Pharmacy pays

~$20.44 /30

$0.05 /mL

Type

OTC

Active ingredient

CODEINE SULFATE

LOPERAMIDE HYDROCHLORIDE

Manufacturer

Hikma

Kenvue Brands

Dosage forms

Tablet

Capsule, Solution, Tablet

Drug class

Opioid Agonist

Boxed warning

None

Half-life

—

about 10.8 hours (range 9.1 to 14.4 hours)

Treats

Cough, Pain

Functional Colonic Diseases, Diarrhea, Bacillary Dysentery

Get imodium a-d

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Frequently asked questions

Which is better-rated, Codeine Sulfate or Imodium A-D?

By our independent rating, Codeine Sulfate scores higher — 3.6 vs 3.5 out of 5 for Imodium A-D. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Codeine Sulfate and Imodium A-D?

Codeine Sulfate contains Codeine Sulfate, while Imodium A-D contains Loperamide Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.