CODEINE SULFATE vs DILAUDID-HP

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CODEINE SULFATE and DILAUDID-HP are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CODEINE SULFATE	DILAUDID-HP
Rating	72/100	68/100
Pharmacy pays	~$20.44 /30	$0.57 /mL
Type	RX	RX
Active ingredient	CODEINE SULFATE	HYDROMORPHONE HYDROCHLORIDE
Manufacturer	Hikma	Fresenius Kabi USA
Dosage forms	Tablet	Injectable
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	Boxed warning
Half-life	—	about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid
Treats	Cough, Pain	Cough, Postoperative Pain

codeine sulfate dilaudid-hp

Rating

72/100

68/100

Pharmacy pays

~$20.44 /30

$0.57 /mL

Type

Active ingredient

CODEINE SULFATE

HYDROMORPHONE HYDROCHLORIDE

Manufacturer

Hikma

Fresenius Kabi USA

Dosage forms

Tablet

Injectable

Drug class

Opioid Agonist

Boxed warning

None

Boxed warning

Half-life

—

about 2.3 hours (terminal elimination half-life after an intravenous dose); after an oral dose the label reports a mean T½ of about 2.6 hours for the 8 mg tablet and 2.8 hours for the oral liquid

Treats

Cough, Pain

Cough, Postoperative Pain

Frequently asked questions

Which is better-rated, Codeine Sulfate or Dilaudid-Hp?

By our independent rating, Codeine Sulfate scores higher — 3.6 vs 3.4 out of 5 for Dilaudid-Hp. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Codeine Sulfate and Dilaudid-Hp?

Codeine Sulfate contains Codeine Sulfate, while Dilaudid-Hp contains Hydromorphone Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.