CODEINE SULFATE vs DEMEROL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CODEINE SULFATE and DEMEROL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CODEINE SULFATE	DEMEROL
Rating	72/100	60/100
Pharmacy pays	~$20.44 /30	$0.16 /mL
Type	RX	RX
Active ingredient	CODEINE SULFATE	MEPERIDINE HYDROCHLORIDE
Manufacturer	Hikma	Hospira
Dosage forms	Tablet	Injectable
Drug class	Opioid Agonist	Opioid Agonist
Boxed warning	None	Boxed warning
Treats	Cough, Pain	Pain

codeine sulfate demerol

Rating

72/100

60/100

Pharmacy pays

~$20.44 /30

$0.16 /mL

Type

Active ingredient

CODEINE SULFATE

MEPERIDINE HYDROCHLORIDE

Manufacturer

Hikma

Hospira

Dosage forms

Tablet

Injectable

Drug class

Opioid Agonist

Boxed warning

None

Boxed warning

Treats

Cough, Pain

Pain

Frequently asked questions

Which is better-rated, Codeine Sulfate or Demerol?

By our independent rating, Codeine Sulfate scores higher — 3.6 vs 3.0 out of 5 for Demerol. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Codeine Sulfate and Demerol?

Codeine Sulfate contains Codeine Sulfate, while Demerol contains Meperidine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.