CLOZARIL vs SECUADO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. CLOZARIL and SECUADO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CLOZARIL	SECUADO
Rating	New	New
Pharmacy pays	~$30.62 /30	~$73.98 /30
Type	RX	RX
Active ingredient	CLOZAPINE	ASENAPINE
Manufacturer	Heritage Life	Hisamitsu
Dosage forms	Tablet	Film, extended release
Drug class	Atypical Antipsychotic	Atypical Antipsychotic
Boxed warning	Boxed warning	Boxed warning
Half-life	about 12 hours at steady state (the label gives a mean elimination half-life of 12 hours, range 4 to 66 hours, after 100 mg twice daily); after a single 75 mg dose the mean is 8 hours (range 4 to 12 hours)	about 24 hours (terminal/elimination half-life)
Treats	Bipolar Disorder, Psychotic Disorders, Schizophrenia	Bipolar Disorder, Schizophrenia

clozaril secuado

Rating

New

Pharmacy pays

~$30.62 /30

~$73.98 /30

Type

Active ingredient

CLOZAPINE

ASENAPINE

Manufacturer

Heritage Life

Hisamitsu

Dosage forms

Tablet

Film, extended release

Drug class

Atypical Antipsychotic

Boxed warning

Half-life

about 12 hours at steady state (the label gives a mean elimination half-life of 12 hours, range 4 to 66 hours, after 100 mg twice daily); after a single 75 mg dose the mean is 8 hours (range 4 to 12 hours)

about 24 hours (terminal/elimination half-life)

Treats

Bipolar Disorder, Psychotic Disorders, Schizophrenia

Bipolar Disorder, Schizophrenia

Frequently asked questions

Which is cheaper, Clozaril or Secuado?

Clozaril costs pharmacies less to acquire — about $30.62 vs $73.98 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Clozaril and Secuado?

Clozaril contains Clozapine, while Secuado contains Asenapine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.