CLONIDINE HYDROCHLORIDE vs NEXCEDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. CLONIDINE HYDROCHLORIDE and NEXCEDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CLONIDINE HYDROCHLORIDE	NEXCEDE
Rating	72/100	70/100
Pharmacy pays	~$1.05 /30	~$193.86 /30
Type	RX	RX
Active ingredient	CLONIDINE HYDROCHLORIDE	KETOPROFEN
Manufacturer	Actavis Elizabeth	Novartis
Dosage forms	Injectable, Tablet, Tablet, extended release	Film
Drug class	Central Alpha-2 Adrenergic Agonist	—
Boxed warning	None	None
Half-life	about 12 to 16 hours	—
Treats	Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea	Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis

clonidine hydrochloride nexcede

Rating

72/100

70/100

Pharmacy pays

~$1.05 /30

~$193.86 /30

Type

Active ingredient

CLONIDINE HYDROCHLORIDE

KETOPROFEN

Manufacturer

Actavis Elizabeth

Novartis

Dosage forms

Injectable, Tablet, Tablet, extended release

Film

Drug class

Central Alpha-2 Adrenergic Agonist

—

Boxed warning

None

Half-life

about 12 to 16 hours

—

Treats

Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea

Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis

Frequently asked questions

Which is better-rated, Clonidine Hydrochloride or Nexcede?

By our independent rating, Clonidine Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Nexcede. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Clonidine Hydrochloride or Nexcede?

Clonidine Hydrochloride costs pharmacies less to acquire — about $1.05 vs $193.86 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Clonidine Hydrochloride and Nexcede?

Clonidine Hydrochloride contains Clonidine Hydrochloride, while Nexcede contains Ketoprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.