CLONIDINE HYDROCHLORIDE vs DYRENIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. CLONIDINE HYDROCHLORIDE and DYRENIUM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CLONIDINE HYDROCHLORIDE	DYRENIUM
Rating	72/100	New
Pharmacy pays	~$1.05 /30	~$211.37 /30
Type	RX	RX
Active ingredient	CLONIDINE HYDROCHLORIDE	TRIAMTERENE
Manufacturer	Actavis Elizabeth	Advanz Pharma
Dosage forms	Injectable, Tablet, Tablet, extended release	Capsule
Drug class	Central Alpha-2 Adrenergic Agonist	Potassium-Sparing Diuretic
Boxed warning	None	Boxed warning
Half-life	about 12 to 16 hours	—
Treats	Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea	Edema, Hypertension, Hypokalemia

clonidine hydrochloride dyrenium

Rating

72/100

New

Pharmacy pays

~$1.05 /30

~$211.37 /30

Type

Active ingredient

CLONIDINE HYDROCHLORIDE

TRIAMTERENE

Manufacturer

Actavis Elizabeth

Advanz Pharma

Dosage forms

Injectable, Tablet, Tablet, extended release

Capsule

Drug class

Central Alpha-2 Adrenergic Agonist

Potassium-Sparing Diuretic

Boxed warning

None

Boxed warning

Half-life

about 12 to 16 hours

—

Treats

Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea

Edema, Hypertension, Hypokalemia

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Frequently asked questions

Which is cheaper, Clonidine Hydrochloride or Dyrenium?

Clonidine Hydrochloride costs pharmacies less to acquire — about $1.05 vs $211.37 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Clonidine Hydrochloride and Dyrenium?

Clonidine Hydrochloride contains Clonidine Hydrochloride, while Dyrenium contains Triamterene — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.