CLONAZEPAM vs DIAZEPAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. CLONAZEPAM and DIAZEPAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CLONAZEPAM	DIAZEPAM
Rating	New	68/100
Pharmacy pays	~$0.83 /30	~$0.87 /30
Type	RX	RX
Active ingredient	CLONAZEPAM	DIAZEPAM
Manufacturer	Rubicon Research	Aurobindo Pharma Ltd
Dosage forms	Tablet, Tablet, orally disintegrating	Injectable, Tablet
Drug class	Benzodiazepine	Benzodiazepine
Boxed warning	Boxed warning	Boxed warning
Half-life	about 30 to 40 hours	about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age
Treats	Bipolar Disorder, Dysarthria, Myoclonic Epilepsies	Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus

clonazepam diazepam

Rating

New

68/100

Pharmacy pays

~$0.83 /30

~$0.87 /30

Type

Active ingredient

CLONAZEPAM

DIAZEPAM

Manufacturer

Rubicon Research

Aurobindo Pharma Ltd

Dosage forms

Tablet, Tablet, orally disintegrating

Injectable, Tablet

Drug class

Benzodiazepine

Boxed warning

Half-life

about 30 to 40 hours

about 48 hours (up to 48 hours), but it varies strongly with age — roughly 20 hours at age 20 and rising by about 1 hour for each year of age

Treats

Bipolar Disorder, Dysarthria, Myoclonic Epilepsies

Alcohol Withdrawal Delirium, Muscle Spasticity, Status Epilepticus

Frequently asked questions

Which is cheaper, Clonazepam or Diazepam?

Clonazepam costs pharmacies less to acquire — about $0.83 vs $0.87 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Clonazepam and Diazepam?

Clonazepam contains Clonazepam, while Diazepam contains Diazepam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.