CLINORIL vs RUFEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CLINORIL and RUFEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CLINORIL	RUFEN
Rating	70/100	70/100
Pharmacy pays	~$6.27 /30	$0.04 /mL
Type	RX	RX
Active ingredient	SULINDAC	IBUPROFEN
Manufacturer	Merck	Basf
Dosage forms	Tablet	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	—	about 1.8 to 2.0 hours
Treats	Rheumatoid Arthritis, Bursitis, Inflammation	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

clinoril rufen

Rating

70/100

Pharmacy pays

~$6.27 /30

$0.04 /mL

Type

Active ingredient

SULINDAC

IBUPROFEN

Manufacturer

Merck

Basf

Dosage forms

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

—

about 1.8 to 2.0 hours

Treats

Rheumatoid Arthritis, Bursitis, Inflammation

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Frequently asked questions

Which is better-rated, Clinoril or Rufen?

Clinoril and Rufen are tied at 3.5 out of 5 by our independent rating.

What is the difference between Clinoril and Rufen?

Clinoril contains Sulindac, while Rufen contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.