CLINORIL vs RELAFEN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CLINORIL and RELAFEN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CLINORIL	RELAFEN
Rating	70/100	New
Pharmacy pays	~$6.27 /30	~$4.00 /30
Type	RX	RX
Active ingredient	SULINDAC	NABUMETONE
Manufacturer	Merck	Smithkline Beecham
Dosage forms	Tablet	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Treats	Rheumatoid Arthritis, Bursitis, Inflammation	Rheumatoid Arthritis, Inflammation, Osteoarthritis

clinoril relafen

Rating

70/100

New

Pharmacy pays

~$6.27 /30

~$4.00 /30

Type

Active ingredient

SULINDAC

NABUMETONE

Manufacturer

Merck

Smithkline Beecham

Dosage forms

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Treats

Rheumatoid Arthritis, Bursitis, Inflammation

Rheumatoid Arthritis, Inflammation, Osteoarthritis

Frequently asked questions

Which is cheaper, Clinoril or Relafen?

Relafen costs pharmacies less to acquire — about $4.00 vs $6.27 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Clinoril and Relafen?

Clinoril contains Sulindac, while Relafen contains Nabumetone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.