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CLINDESSE vs SEPTI-SOFT

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CLINDESSE and SEPTI-SOFT are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
New

Pharmacy pays

$0.18 /g

Type

RX
RX

Active ingredient

CLINDAMYCIN PHOSPHATE
HEXACHLOROPHENE

Manufacturer

Dosage forms

Topical
Solution

Drug class

Lincosamide Antibacterial

Boxed warning

None
None

Half-life

about 2.4 hours

Treats

Acne Vulgaris, Actinomycetales Infections, Bacteroides Infections
Acne Vulgaris

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Frequently asked questions

What is the difference between Clindesse and Septi-Soft?

Clindesse contains Clindamycin Phosphate, while Septi-Soft contains Hexachlorophene — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.