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CLIMARA vs FEMRING

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. CLIMARA and FEMRING are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

New
New

Pharmacy pays

$6.55 /g
$6.55 /g

Type

RX
RX

Active ingredient

ESTRADIOL
ESTRADIOL ACETATE

Dosage forms

Patch
Ring

Drug class

Estrogen
Estrogen

Treats

Breast Neoplasms, Hypogonadism, Premature Menopause
Breast Neoplasms, Hypogonadism, Premature Menopause

Frequently asked questions

Which is cheaper, Climara or Femring?

Pharmacies pay about the same to acquire either one — roughly $6.55 per gm, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Climara and Femring?

Climara contains Estradiol, while Femring contains Estradiol Acetate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.