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CLEOCIN vs CLINDAMYCIN HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. CLEOCIN and CLINDAMYCIN HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

64/100
New

Pharmacy pays

$0.18 /g
$0.18 /g

Type

RX
RX

Active ingredient

CLINDAMYCIN PHOSPHATE
CLINDAMYCIN HYDROCHLORIDE

Dosage forms

Topical, Suppository
Capsule

Drug class

Lincosamide Antibacterial
Lincosamide Antibacterial

Boxed warning

Half-life

about 2.4 hours
about 2.4 hours

Treats

Acne Vulgaris, Actinomycetales Infections, Bacteroides Infections
Acne Vulgaris, Actinomycetales Infections, Bacteroides Infections

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Frequently asked questions

Which is cheaper, Cleocin or Clindamycin Hydrochloride?

Pharmacies pay about the same to acquire either one — roughly $0.18 per gm, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Cleocin and Clindamycin Hydrochloride?

Cleocin contains Clindamycin Phosphate, while Clindamycin Hydrochloride contains Clindamycin Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.