CLARITIN-D vs CLARITIN-D 24 HOUR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Attribute	CLARITIN-D	CLARITIN-D 24 HOUR
Rating	68/100	68/100
Pharmacy pays	~$1.60 /30	~$1.60 /30
Type	OTC	OTC
Active ingredient	LORATADINE AND PSEUDOEPHEDRINE SULFATE	LORATADINE AND PSEUDOEPHEDRINE SULFATE
Manufacturer	Bayer Pharms	Bayer Pharms
Dosage forms	Tablet, extended release	Tablet, extended release
Drug class	—	—
Boxed warning	None	None
Half-life	roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)	roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

claritin-d claritin-d 24 hour

Rating

68/100

Pharmacy pays

~$1.60 /30

Type

OTC

Active ingredient

LORATADINE AND PSEUDOEPHEDRINE SULFATE

Manufacturer

Bayer Pharms

Dosage forms

Tablet, extended release

Drug class

—

Boxed warning

None

Half-life

roughly 3 to 16 hours — the label does not give one number, because the elimination half-life depends on urine pH: about 3 to 6 hours when urine pH is 5 (acidic), and about 9 to 16 hours when urine pH is 8 (alkaline)

Get claritin-dhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Where to buy

Buy over-the-counter from trusted retailers.

AmazonCheck price on Amazon

Frequently asked questions

Which is better-rated, Claritin-D or Claritin-D 24 Hour?

Claritin-D and Claritin-D 24 Hour are tied at 3.4 out of 5 by our independent rating.

Which is cheaper, Claritin-D or Claritin-D 24 Hour?

Pharmacies pay about the same to acquire either one — roughly $1.60 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Claritin-D and Claritin-D 24 Hour?

Both Claritin-D and Claritin-D 24 Hour share the active ingredient Loratadine and Pseudoephedrine Sulfate.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.