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CITALOPRAM HYDROBROMIDE vs PAROXETINE MESYLATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CITALOPRAM HYDROBROMIDE and PAROXETINE MESYLATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

68/100
70/100

Pharmacy pays

~$2.84 /30

Type

RX
RX

Active ingredient

CITALOPRAM HYDROBROMIDE
PAROXETINE MESYLATE

Dosage forms

Tablet
Capsule

Drug class

Serotonin Reuptake Inhibitor
Serotonin Reuptake Inhibitor

Boxed warning

Half-life

about 35 hours
about 21 hours on average (the label reports a mean of approximately 21 hours, with 32% variability between people)

Treats

Alcoholism, Dementia, Depressive Disorder
Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

Get paroxetine mesylatehigher-rated option

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Frequently asked questions

Which is better-rated, Citalopram Hydrobromide or Paroxetine Mesylate?

By our independent rating, Paroxetine Mesylate scores higher — 3.5 vs 3.4 out of 5 for Citalopram Hydrobromide. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Citalopram Hydrobromide and Paroxetine Mesylate?

Citalopram Hydrobromide contains Citalopram Hydrobromide, while Paroxetine Mesylate contains Paroxetine Mesylate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.