CIMETIDINE HYDROCHLORIDE vs FAMOTIDINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CIMETIDINE HYDROCHLORIDE and FAMOTIDINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CIMETIDINE HYDROCHLORIDE	FAMOTIDINE
Rating	New	70/100
Pharmacy pays	~$9.92 /30	~$1.54 /30
Type	RX	RX
Active ingredient	CIMETIDINE HYDROCHLORIDE	FAMOTIDINE
Manufacturer	Chartwell Molecular	Micro Labs
Dosage forms	Solution	Injectable, Solution, Powder, Tablet
Drug class	Histamine-2 Receptor Antagonist	Histamine-2 Receptor Antagonist
Boxed warning	None	None
Half-life	—	2.5 to 3.5 hours
Treats	Duodenal Ulcer, Dyspepsia, Peptic Esophagitis	Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

cimetidine hydrochloride famotidine

Rating

New

70/100

Pharmacy pays

~$9.92 /30

~$1.54 /30

Type

Active ingredient

CIMETIDINE HYDROCHLORIDE

FAMOTIDINE

Manufacturer

Chartwell Molecular

Micro Labs

Dosage forms

Solution

Injectable, Solution, Powder, Tablet

Drug class

Histamine-2 Receptor Antagonist

Boxed warning

None

Half-life

—

2.5 to 3.5 hours

Treats

Duodenal Ulcer, Dyspepsia, Peptic Esophagitis

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Frequently asked questions

Which is cheaper, Cimetidine Hydrochloride or Famotidine?

Famotidine costs pharmacies less to acquire — about $1.54 vs $9.92 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cimetidine Hydrochloride and Famotidine?

Cimetidine Hydrochloride contains Cimetidine Hydrochloride, while Famotidine contains Famotidine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.