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CHLORZOXAZONE vs SKELAXIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. CHLORZOXAZONE and SKELAXIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

chlorzoxazoneskelaxin

Rating

70/100
New

Pharmacy pays

~$16.14 /30
~$11.97 /30

Type

RX
RX

Active ingredient

CHLORZOXAZONE
METAXALONE

Manufacturer

Ohm Labs
King Pharms LLC

Dosage forms

Tablet
Tablet

Drug class

Muscle Relaxant
Muscle Relaxant

Boxed warning

None
None

Half-life

—
about 9 hours (terminal half-life 9.0 ± 4.8 hours after a 400 mg oral dose, fasted; ~8 hours at 800 mg)

Treats

Muscle Cramp, Muscle Rigidity, Myositis
Muscle Cramp, Muscle Rigidity, Muscle Spasticity

Frequently asked questions

Which is cheaper, Chlorzoxazone or Skelaxin?

Skelaxin costs pharmacies less to acquire — about $11.97 vs $16.14 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Chlorzoxazone and Skelaxin?

Chlorzoxazone contains Chlorzoxazone, while Skelaxin contains Metaxalone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.