CHLORPHENIRAMINE MALEATE vs XYZAL ALLERGY 24HR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 11, 2026·How we rate

Attribute	CHLORPHENIRAMINE MALEATE	XYZAL ALLERGY 24HR
Rating	70/100	New
Pharmacy pays	—	$0.06 /mL
Type	RX	OTC
Active ingredient	CHLORPHENIRAMINE MALEATE	LEVOCETIRIZINE DIHYDROCHLORIDE
Manufacturer	Roxane	Chattem Sanofi
Dosage forms	Tablet	Tablet
Drug class	Histamine-1 Receptor Antagonist	Histamine-1 Receptor Antagonist
Boxed warning	None	None
Treats	Perennial Allergic Rhinitis, Urticaria	Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria

chlorpheniramine maleate xyzal allergy 24hr

Rating

70/100

New

Pharmacy pays

—

$0.06 /mL

Type

OTC

Active ingredient

CHLORPHENIRAMINE MALEATE

LEVOCETIRIZINE DIHYDROCHLORIDE

Manufacturer

Roxane

Chattem Sanofi

Dosage forms

Tablet

Drug class

Histamine-1 Receptor Antagonist

Boxed warning

None

Treats

Perennial Allergic Rhinitis, Urticaria

Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

What is the difference between Chlorpheniramine Maleate and Xyzal Allergy 24hr?

Chlorpheniramine Maleate contains Chlorpheniramine Maleate, while Xyzal Allergy 24hr contains Levocetirizine Dihydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.