CHLORPHENIRAMINE MALEATE vs FEXOFENADINE HYDROCHLORIDE HIVES

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Attribute	CHLORPHENIRAMINE MALEATE	FEXOFENADINE HYDROCHLORIDE HIVES
Rating	70/100	New
Pharmacy pays	—	~$7.22 /30
Type	RX	OTC
Active ingredient	CHLORPHENIRAMINE MALEATE	FEXOFENADINE HYDROCHLORIDE
Manufacturer	Roxane	Sun Pharm Inds Inc
Dosage forms	Tablet	Tablet
Drug class	Histamine-1 Receptor Antagonist	Histamine-1 Receptor Antagonist
Boxed warning	None	None
Half-life	—	about 14 hours (label: mean elimination half-life 14.4 hours)
Treats	Perennial Allergic Rhinitis, Urticaria	Perennial Allergic Rhinitis, Urticaria

chlorpheniramine maleate fexofenadine hydrochloride hives

Rating

70/100

New

Pharmacy pays

—

~$7.22 /30

Type

OTC

Active ingredient

CHLORPHENIRAMINE MALEATE

FEXOFENADINE HYDROCHLORIDE

Manufacturer

Roxane

Sun Pharm Inds Inc

Dosage forms

Tablet

Drug class

Histamine-1 Receptor Antagonist

Boxed warning

None

Half-life

—

about 14 hours (label: mean elimination half-life 14.4 hours)

Treats

Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

What is the difference between Chlorpheniramine Maleate and Fexofenadine Hydrochloride Hives?

Chlorpheniramine Maleate contains Chlorpheniramine Maleate, while Fexofenadine Hydrochloride Hives contains Fexofenadine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.