CHLOROQUINE PHOSPHATE vs PLAQUENIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CHLOROQUINE PHOSPHATE and PLAQUENIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CHLOROQUINE PHOSPHATE	PLAQUENIL
Rating	70/100	New
Pharmacy pays	—	~$4.86 /30
Type	RX	RX
Active ingredient	CHLOROQUINE PHOSPHATE	HYDROXYCHLOROQUINE SULFATE
Manufacturer	Impax	Advanz Pharma
Dosage forms	Tablet	Tablet
Drug class	Antimalarial	Antimalarial
Boxed warning	None	None
Half-life	—	about 40 to 50 days (terminal elimination half-life in whole blood)
Treats	Amebiasis, Rheumatoid Arthritis, Discoid Lupus Erythematosus	Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria

chloroquine phosphate plaquenil

Rating

70/100

New

Pharmacy pays

—

~$4.86 /30

Type

Active ingredient

CHLOROQUINE PHOSPHATE

HYDROXYCHLOROQUINE SULFATE

Manufacturer

Impax

Advanz Pharma

Dosage forms

Tablet

Drug class

Antimalarial

Boxed warning

None

Half-life

—

about 40 to 50 days (terminal elimination half-life in whole blood)

Treats

Amebiasis, Rheumatoid Arthritis, Discoid Lupus Erythematosus

Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria

Frequently asked questions

What is the difference between Chloroquine Phosphate and Plaquenil?

Chloroquine Phosphate contains Chloroquine Phosphate, while Plaquenil contains Hydroxychloroquine Sulfate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.