CHLORHEXIDINE GLUCONATE vs NYSTATIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Attribute	CHLORHEXIDINE GLUCONATE	NYSTATIN
Rating	70/100	68/100
Pharmacy pays	—	$0.25 /g
Type	OTC	RX
Active ingredient	CHLORHEXIDINE GLUCONATE	NYSTATIN
Manufacturer	Becton Dickinson Co	Sandoz
Dosage forms	Rinse, Cloth, Topical, Liquid, Solution	Topical, Powder, Suspension, Tablet
Drug class	—	Polyene Antifungal
Boxed warning	None	None
Treats	Oral Candidiasis, Periodontal Diseases, Infectious Skin Diseases	Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis, Oral Candidiasis

chlorhexidine gluconate nystatin

Rating

70/100

68/100

Pharmacy pays

—

$0.25 /g

Type

OTC

Active ingredient

CHLORHEXIDINE GLUCONATE

NYSTATIN

Manufacturer

Becton Dickinson Co

Sandoz

Dosage forms

Rinse, Cloth, Topical, Liquid, Solution

Topical, Powder, Suspension, Tablet

Drug class

—

Polyene Antifungal

Boxed warning

None

Treats

Oral Candidiasis, Periodontal Diseases, Infectious Skin Diseases

Chronic Mucocutaneous Candidiasis, Cutaneous Candidiasis, Oral Candidiasis

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Frequently asked questions

Which is better-rated, Chlorhexidine Gluconate or Nystatin?

By our independent rating, Chlorhexidine Gluconate scores higher — 3.5 vs 3.4 out of 5 for Nystatin. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Chlorhexidine Gluconate and Nystatin?

Chlorhexidine Gluconate contains Chlorhexidine Gluconate, while Nystatin contains Nystatin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.