CHILDREN'S MOTRIN vs LODINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CHILDREN'S MOTRIN and LODINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CHILDREN'S MOTRIN	LODINE
Rating	70/100	New
Pharmacy pays	$0.04 /mL	~$22.58 /30
Type	RX	RX
Active ingredient	IBUPROFEN	ETODOLAC
Manufacturer	Kenvue Brands	Wyeth Pharms Inc
Dosage forms	Tablet, chewable, Drops, Suspension	Tablet, Capsule
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	about 1.8 to 2.0 hours	about 6.4 hours (roughly 6 to 8 hours; label reports a mean terminal half-life of 6.4 hours with 22% coefficient of variation)
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	Rheumatoid Arthritis, Osteoarthritis, Pain

children's motrin lodine

Rating

70/100

New

Pharmacy pays

$0.04 /mL

~$22.58 /30

Type

Active ingredient

IBUPROFEN

ETODOLAC

Manufacturer

Kenvue Brands

Wyeth Pharms Inc

Dosage forms

Tablet, chewable, Drops, Suspension

Tablet, Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 1.8 to 2.0 hours

about 6.4 hours (roughly 6 to 8 hours; label reports a mean terminal half-life of 6.4 hours with 22% coefficient of variation)

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Rheumatoid Arthritis, Osteoarthritis, Pain

Frequently asked questions

What is the difference between Children's Motrin and Lodine?

Children's Motrin contains Ibuprofen, while Lodine contains Etodolac — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.