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CHILDREN'S ASTEPRO ALLERGY vs CHILDREN'S ZYRTEC ALLERGY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Rating

New
70/100

Pharmacy pays

$0.58 /mL
$0.06 /mL

Type

OTC
OTC

Active ingredient

AZELASTINE HYDROCHLORIDE
CETIRIZINE HYDROCHLORIDE

Dosage forms

Spray/Inhaler, metered
Solution, Syrup

Drug class

Histamine-1 Receptor Antagonist
Histamine-1 Receptor Antagonist

Boxed warning

None
None

Half-life

about 8.3 hours (mean in healthy adults)

Treats

Allergic Conjunctivitis, Perennial Allergic Rhinitis, Vasomotor Rhinitis
Perennial Allergic Rhinitis, Urticaria

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is cheaper, Children's Astepro Allergy or Children's Zyrtec Allergy?

Children's Zyrtec Allergy costs pharmacies less to acquire — about $0.06 vs $0.58 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Children's Astepro Allergy and Children's Zyrtec Allergy?

Children's Astepro Allergy contains Azelastine Hydrochloride, while Children's Zyrtec Allergy contains Cetirizine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.