CHILDREN'S ALLEGRA HIVES vs CHILDREN'S ZYRTEC ALLERGY

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Attribute	CHILDREN'S ALLEGRA HIVES	CHILDREN'S ZYRTEC ALLERGY
Rating	New	70/100
Pharmacy pays	~$7.33 /30	$0.06 /mL
Type	RX	OTC
Active ingredient	FEXOFENADINE HYDROCHLORIDE	CETIRIZINE HYDROCHLORIDE
Manufacturer	Chattem Sanofi	Kenvue Brands
Dosage forms	Tablet, orally disintegrating	Solution, Syrup
Drug class	Histamine-1 Receptor Antagonist	Histamine-1 Receptor Antagonist
Boxed warning	None	None
Half-life	about 14 hours (label: mean elimination half-life 14.4 hours)	about 8.3 hours (mean in healthy adults)
Treats	Perennial Allergic Rhinitis, Urticaria	Perennial Allergic Rhinitis, Urticaria

children's allegra hives children's zyrtec allergy

Rating

New

70/100

Pharmacy pays

~$7.33 /30

$0.06 /mL

Type

OTC

Active ingredient

FEXOFENADINE HYDROCHLORIDE

CETIRIZINE HYDROCHLORIDE

Manufacturer

Chattem Sanofi

Kenvue Brands

Dosage forms

Tablet, orally disintegrating

Solution, Syrup

Drug class

Histamine-1 Receptor Antagonist

Boxed warning

None

Half-life

about 14 hours (label: mean elimination half-life 14.4 hours)

about 8.3 hours (mean in healthy adults)

Treats

Perennial Allergic Rhinitis, Urticaria

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Frequently asked questions

What is the difference between Children's Allegra Hives and Children's Zyrtec Allergy?

Children's Allegra Hives contains Fexofenadine Hydrochloride, while Children's Zyrtec Allergy contains Cetirizine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.