CEQUA vs PROTOPIC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. CEQUA and PROTOPIC are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CEQUA	PROTOPIC
Rating	New	New
Pharmacy pays	~$52.85 /30	$0.65 /g
Type	RX	RX
Active ingredient	CYCLOSPORINE	TACROLIMUS
Manufacturer	Sun Pharm	Leo Pharma As
Dosage forms	Drops	Topical
Drug class	Calcineurin Inhibitor Immunosuppressant	Calcineurin Inhibitor Immunosuppressant
Boxed warning	None	None
Half-life	about 8.4 hours (range 5 to 18 hours)	—
Treats	Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus	Atopic Dermatitis, Graft Vs Host Disease

cequa protopic

Rating

New

Pharmacy pays

~$52.85 /30

$0.65 /g

Type

Active ingredient

CYCLOSPORINE

TACROLIMUS

Manufacturer

Sun Pharm

Leo Pharma As

Dosage forms

Drops

Topical

Drug class

Calcineurin Inhibitor Immunosuppressant

Boxed warning

None

Half-life

about 8.4 hours (range 5 to 18 hours)

—

Treats

Rheumatoid Arthritis, Focal Segmental Glomerulosclerosis, Systemic Lupus Erythematosus

Atopic Dermatitis, Graft Vs Host Disease

Frequently asked questions

What is the difference between Cequa and Protopic?

Cequa contains Cyclosporine, while Protopic contains Tacrolimus — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.