CELONTIN vs DEPAKOTE ER

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CELONTIN and DEPAKOTE ER are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CELONTIN	DEPAKOTE ER
Rating	New	70/100
Pharmacy pays	—	~$5.99 /30
Type	RX	RX
Active ingredient	METHSUXIMIDE	DIVALPROEX SODIUM
Manufacturer	Parke Davis	Abbott
Dosage forms	Capsule	Tablet, extended release
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	None	None
Half-life	—	about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)
Treats	Absence Epilepsy	Bipolar Disorder, Epilepsy, Absence Epilepsy

celontin depakote er

Rating

New

70/100

Pharmacy pays

—

~$5.99 /30

Type

Active ingredient

METHSUXIMIDE

DIVALPROEX SODIUM

Manufacturer

Parke Davis

Abbott

Dosage forms

Capsule

Tablet, extended release

Drug class

Anti-Epileptic Agent

Boxed warning

None

Half-life

—

about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)

Treats

Absence Epilepsy

Bipolar Disorder, Epilepsy, Absence Epilepsy

Frequently asked questions

What is the difference between Celontin and Depakote ER?

Celontin contains Methsuximide, while Depakote ER contains Divalproex Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.