CELONTIN vs DEPAKOTE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 20, 2026·How we rate

Possible drug interaction. CELONTIN and DEPAKOTE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CELONTIN	DEPAKOTE
Rating	New	72/100
Pharmacy pays	—	~$5.99 /30
Type	RX	RX
Active ingredient	METHSUXIMIDE	DIVALPROEX SODIUM
Manufacturer	Parke Davis	Abbvie
Dosage forms	Capsule	Tablet, delayed release
Drug class	Anti-Epileptic Agent	Anti-Epileptic Agent
Boxed warning	None	Boxed warning
Half-life	—	about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)
Treats	Absence Epilepsy	Bipolar Disorder, Epilepsy, Absence Epilepsy

celontin depakote

Rating

New

72/100

Pharmacy pays

—

~$5.99 /30

Type

Active ingredient

METHSUXIMIDE

DIVALPROEX SODIUM

Manufacturer

Parke Davis

Abbvie

Dosage forms

Capsule

Tablet, delayed release

Drug class

Anti-Epileptic Agent

Boxed warning

None

Boxed warning

Half-life

—

about 9 to 16 hours (the label's mean terminal half-life range for valproate monotherapy)

Treats

Absence Epilepsy

Bipolar Disorder, Epilepsy, Absence Epilepsy

Frequently asked questions

What is the difference between Celontin and Depakote?

Celontin contains Methsuximide, while Depakote contains Divalproex Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.