CELECOXIB vs PENNSAID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Possible drug interaction. CELECOXIB and PENNSAID are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CELECOXIB	PENNSAID
Rating	64/100	New
Pharmacy pays	~$2.51 /30	$0.36 /mL
Type	RX	RX
Active ingredient	CELECOXIB	DICLOFENAC SODIUM
Manufacturer	Lupin	Horizon
Dosage forms	Capsule	Solution
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	None
Half-life	about 11 hours	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
Treats	Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

celecoxib pennsaid

Rating

64/100

New

Pharmacy pays

~$2.51 /30

$0.36 /mL

Type

Active ingredient

CELECOXIB

DICLOFENAC SODIUM

Manufacturer

Lupin

Horizon

Dosage forms

Capsule

Solution

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 11 hours

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

Treats

Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Frequently asked questions

What is the difference between Celecoxib and Pennsaid?

Celecoxib contains Celecoxib, while Pennsaid contains Diclofenac Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.