CELEBREX vs DICLOFENAC SODIUM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. CELEBREX and DICLOFENAC SODIUM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CELEBREX	DICLOFENAC SODIUM
Rating	New	70/100
Pharmacy pays	~$2.51 /30	$0.36 /mL
Type	RX	RX
Active ingredient	CELECOXIB	DICLOFENAC SODIUM
Manufacturer	Gd Searle LLC	Amneal
Dosage forms	Capsule	Solution, Drops, Topical, Tablet, delayed release, Tablet, extended release, Tablet, Kit
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	Boxed warning
Half-life	about 11 hours	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
Treats	Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

celebrex diclofenac sodium

Rating

New

70/100

Pharmacy pays

~$2.51 /30

$0.36 /mL

Type

Active ingredient

CELECOXIB

DICLOFENAC SODIUM

Manufacturer

Gd Searle LLC

Amneal

Dosage forms

Capsule

Solution, Drops, Topical, Tablet, delayed release, Tablet, extended release, Tablet, Kit

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 11 hours

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

Treats

Rheumatoid Arthritis, Dysmenorrhea, Osteoarthritis

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Frequently asked questions

What is the difference between Celebrex and Diclofenac Sodium?

Celebrex contains Celecoxib, while Diclofenac Sodium contains Diclofenac Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.