CEFOTAN vs NITROFURANTOIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 9, 2026·How we rate

Possible drug interaction. CEFOTAN and NITROFURANTOIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CEFOTAN	NITROFURANTOIN
Rating	72/100	72/100
Pharmacy pays	—	$2.02 /mL
Type	RX	RX
Active ingredient	CEFOTETAN DISODIUM	NITROFURANTOIN
Manufacturer	Pai Holdings Pharm	Amneal
Dosage forms	Injectable	Capsule, Suspension
Drug class	Cephalosporin Antibacterial	Nitrofuran Antibacterial
Boxed warning	None	None
Half-life	—	about 20 minutes (roughly 0.3 hours) for the parent drug in adults with normal kidney function
Treats	Abscess, Bacteroides Infections, Human Bites	Escherichia Coli Infections, Klebsiella Infections, Staphylococcal Infections

cefotan nitrofurantoin

Rating

72/100

Pharmacy pays

—

$2.02 /mL

Type

Active ingredient

CEFOTETAN DISODIUM

NITROFURANTOIN

Manufacturer

Pai Holdings Pharm

Amneal

Dosage forms

Injectable

Capsule, Suspension

Drug class

Cephalosporin Antibacterial

Nitrofuran Antibacterial

Boxed warning

None

Half-life

—

about 20 minutes (roughly 0.3 hours) for the parent drug in adults with normal kidney function

Treats

Abscess, Bacteroides Infections, Human Bites

Escherichia Coli Infections, Klebsiella Infections, Staphylococcal Infections

Get nitrofurantoin

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is better-rated, Cefotan or Nitrofurantoin?

Cefotan and Nitrofurantoin are tied at 3.6 out of 5 by our independent rating.

What is the difference between Cefotan and Nitrofurantoin?

Cefotan contains Cefotetan Disodium, while Nitrofurantoin contains Nitrofurantoin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.