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CATHFLO ACTIVASE vs COUMADIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Possible drug interaction. CATHFLO ACTIVASE and COUMADIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
72/100

Pharmacy pays

~$2.58 /30

Type

RX
RX

Active ingredient

ALTEPLASE
WARFARIN SODIUM

Dosage forms

Injectable
Tablet

Drug class

Vitamin K Antagonist

Boxed warning

None
None

Half-life

about 40 hours (the label's effective half-life; range 20 to 60 hours)

Treats

Arterial Occlusive Diseases, Intracranial Embolism and Thrombosis, Myocardial Infarction
Atrial Fibrillation, Postoperative Complications, Pulmonary Embolism

Frequently asked questions

Which is better-rated, Cathflo Activase or Coumadin?

By our independent rating, Coumadin scores higher — 3.6 vs 3.5 out of 5 for Cathflo Activase. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cathflo Activase and Coumadin?

Cathflo Activase contains Alteplase, while Coumadin contains Warfarin Sodium — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.