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CATAPRES-TTS-3 vs ZANAFLEX

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. CATAPRES-TTS-3 and ZANAFLEX are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

catapres-tts-3zanaflex

Rating

New
New

Pharmacy pays

~$1.05 /30
~$1.00 /30

Type

RX
RX

Active ingredient

CLONIDINE
TIZANIDINE HYDROCHLORIDE

Manufacturer

Lavipharm
Legacy Pharma

Dosage forms

Patch
Capsule, Tablet

Drug class

Central Alpha-2 Adrenergic Agonist
Central Alpha-2 Adrenergic Agonist

Boxed warning

None
None

Half-life

about 12 to 16 hours
about 2.5 hours

Treats

Attention Deficit Disorder with Hyperactivity, Diarrhea, Dysmenorrhea
Muscle Cramp, Muscle Rigidity, Muscle Spasticity

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Frequently asked questions

Which is cheaper, Catapres-Tts-3 or Zanaflex?

Zanaflex costs pharmacies less to acquire — about $1.00 vs $1.05 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Catapres-Tts-3 and Zanaflex?

Catapres-Tts-3 contains Clonidine, while Zanaflex contains Tizanidine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.