CATAFLAM vs MOTRIN MIGRAINE PAIN

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CATAFLAM and MOTRIN MIGRAINE PAIN are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CATAFLAM	MOTRIN MIGRAINE PAIN
Rating	70/100	70/100
Pharmacy pays	$0.36 /mL	$0.04 /mL
Type	RX	RX
Active ingredient	DICLOFENAC POTASSIUM	IBUPROFEN
Manufacturer	Novartis	Kenvue Brands
Dosage forms	Tablet	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	None	None
Half-life	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)	about 1.8 to 2.0 hours
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

cataflam motrin migraine pain

Rating

70/100

Pharmacy pays

$0.36 /mL

$0.04 /mL

Type

Active ingredient

DICLOFENAC POTASSIUM

IBUPROFEN

Manufacturer

Novartis

Kenvue Brands

Dosage forms

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

about 1.8 to 2.0 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Frequently asked questions

Which is better-rated, Cataflam or Motrin Migraine Pain?

Cataflam and Motrin Migraine Pain are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Cataflam or Motrin Migraine Pain?

Motrin Migraine Pain costs pharmacies less to acquire — about $0.04 vs $0.36 per ml, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cataflam and Motrin Migraine Pain?

Cataflam contains Diclofenac Potassium, while Motrin Migraine Pain contains Ibuprofen — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.