CASODEX vs XTANDI

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. CASODEX and XTANDI are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CASODEX	XTANDI
Rating	70/100	72/100
Pharmacy pays	~$12.17 /30	—
Type	RX	RX
Active ingredient	BICALUTAMIDE	ENZALUTAMIDE
Manufacturer	Astrazeneca	Astellas
Dosage forms	Tablet	Tablet, Capsule
Drug class	Androgen Receptor Inhibitor	Androgen Receptor Inhibitor
Boxed warning	None	None
Treats	Prostatic Neoplasms	Prostatic Neoplasms

casodex xtandi

Rating

70/100

72/100

Pharmacy pays

~$12.17 /30

—

Type

Active ingredient

BICALUTAMIDE

ENZALUTAMIDE

Manufacturer

Astrazeneca

Astellas

Dosage forms

Tablet

Tablet, Capsule

Drug class

Androgen Receptor Inhibitor

Boxed warning

None

Treats

Prostatic Neoplasms

Frequently asked questions

Which is better-rated, Casodex or Xtandi?

By our independent rating, Xtandi scores higher — 3.6 vs 3.5 out of 5 for Casodex. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Casodex and Xtandi?

Casodex contains Bicalutamide, while Xtandi contains Enzalutamide — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.