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CARBIDOPA AND LEVODOPA vs SINEMET CR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Rating

70/100
70/100

Pharmacy pays

~$20.52 /30
~$20.52 /30

Type

RX
RX

Active ingredient

CARBIDOPA AND LEVODOPA
CARBIDOPA AND LEVODOPA

Manufacturer

Dosage forms

Tablet, Tablet, extended release, Tablet, orally disintegrating
Tablet, extended release

Drug class

Boxed warning

None
None

Half-life

about 50 minutes (extended to about 1.5 hours when taken with carbidopa)
about 50 minutes (extended to about 1.5 hours when taken with carbidopa)

Frequently asked questions

Which is better-rated, Carbidopa and Levodopa or Sinemet CR?

Carbidopa and Levodopa and Sinemet CR are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Carbidopa and Levodopa or Sinemet CR?

Pharmacies pay about the same to acquire either one — roughly $20.52 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Carbidopa and Levodopa and Sinemet CR?

Both Carbidopa and Levodopa and Sinemet CR share the active ingredient Carbidopa and Levodopa.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.