CARAFATE vs ZANTAC

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. CARAFATE and ZANTAC are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CARAFATE	ZANTAC
Rating	72/100	72/100
Pharmacy pays	~$5.36 /30	—
Type	RX	RX
Active ingredient	SUCRALFATE	RANITIDINE HYDROCHLORIDE
Manufacturer	Abbvie	Pai Holdings Pharm
Dosage forms	Tablet, Suspension	Injectable, Syrup
Drug class	Aluminum Complex	—
Boxed warning	None	None
Half-life	—	about 2.5 to 3 hours
Treats	Duodenal Ulcer, Esophagitis, Gastritis	Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux

carafate zantac

Rating

72/100

Pharmacy pays

~$5.36 /30

—

Type

Active ingredient

SUCRALFATE

RANITIDINE HYDROCHLORIDE

Manufacturer

Abbvie

Pai Holdings Pharm

Dosage forms

Tablet, Suspension

Injectable, Syrup

Drug class

Aluminum Complex

—

Boxed warning

None

Half-life

—

about 2.5 to 3 hours

Treats

Duodenal Ulcer, Esophagitis, Gastritis

Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux

Frequently asked questions

Which is better-rated, Carafate or Zantac?

Carafate and Zantac are tied at 3.6 out of 5 by our independent rating.

What is the difference between Carafate and Zantac?

Carafate contains Sucralfate, while Zantac contains Ranitidine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.