CAPOZIDE 50/25 vs CUPRIMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 7, 2026·How we rate

Possible drug interaction. CAPOZIDE 50/25 and CUPRIMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CAPOZIDE 50/25	CUPRIMINE
Rating	New	74/100
Pharmacy pays	~$8.51 /30	—
Type	RX	RX
Active ingredient	CAPTOPRIL AND HYDROCHLOROTHIAZIDE	PENICILLAMINE
Manufacturer	Apothecon	Valeant Pharm Intl
Dosage forms	Tablet	Capsule
Drug class	—	Antirheumatic Agent
Boxed warning	None	Boxed warning
Half-life	about 6 to 15 hours (the label reports a range, not a single number)	—
Treats	—	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

capozide 50/25 cuprimine

Rating

New

74/100

Pharmacy pays

~$8.51 /30

—

Type

Active ingredient

CAPTOPRIL AND HYDROCHLOROTHIAZIDE

PENICILLAMINE

Manufacturer

Apothecon

Valeant Pharm Intl

Dosage forms

Tablet

Capsule

Drug class

—

Antirheumatic Agent

Boxed warning

None

Boxed warning

Half-life

about 6 to 15 hours (the label reports a range, not a single number)

—

Treats

—

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

Frequently asked questions

What is the difference between Capozide 50/25 and Cuprimine?

Capozide 50/25 contains Captopril and Hydrochlorothiazide, while Cuprimine contains Penicillamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.