CALQUENCE vs SPRYCEL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 14, 2026·How we rate

Possible drug interaction. CALQUENCE and SPRYCEL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CALQUENCE	SPRYCEL
Rating	70/100	72/100
Pharmacy pays	—	~$839.19 /30
Type	RX	RX
Active ingredient	ACALABRUTINIB	DASATINIB
Manufacturer	Astrazeneca	Bristol Myers Squibb
Dosage forms	Capsule, Tablet	Tablet
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	None
Treats	Mantle-Cell Lymphoma	Lymphoid Leukemia, Myeloid Leukemia

calquence sprycel

Rating

70/100

72/100

Pharmacy pays

—

~$839.19 /30

Type

Active ingredient

ACALABRUTINIB

DASATINIB

Manufacturer

Astrazeneca

Bristol Myers Squibb

Dosage forms

Capsule, Tablet

Tablet

Drug class

Kinase Inhibitor

Boxed warning

None

Treats

Mantle-Cell Lymphoma

Lymphoid Leukemia, Myeloid Leukemia

Frequently asked questions

Which is better-rated, Calquence or Sprycel?

By our independent rating, Sprycel scores higher — 3.6 vs 3.5 out of 5 for Calquence. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Calquence and Sprycel?

Calquence contains Acalabrutinib, while Sprycel contains Dasatinib — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.