CALQUENCE vs ICLUSIG

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 11, 2026·How we rate

Possible drug interaction. CALQUENCE and ICLUSIG are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CALQUENCE	ICLUSIG
Rating	70/100	New
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	ACALABRUTINIB	PONATINIB HYDROCHLORIDE
Manufacturer	Astrazeneca	Takeda Pharms USA
Dosage forms	Capsule, Tablet	Tablet
Drug class	Kinase Inhibitor	Kinase Inhibitor
Boxed warning	None	Boxed warning
Treats	Mantle-Cell Lymphoma	Myeloid Leukemia

calquence iclusig

Rating

70/100

New

Pharmacy pays

—

Type

Active ingredient

ACALABRUTINIB

PONATINIB HYDROCHLORIDE

Manufacturer

Astrazeneca

Takeda Pharms USA

Dosage forms

Capsule, Tablet

Tablet

Drug class

Kinase Inhibitor

Boxed warning

None

Boxed warning

Treats

Mantle-Cell Lymphoma

Myeloid Leukemia

Frequently asked questions

What is the difference between Calquence and Iclusig?

Calquence contains Acalabrutinib, while Iclusig contains Ponatinib Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.