CALDOLOR vs PIROXICAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. CALDOLOR and PIROXICAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CALDOLOR	PIROXICAM
Rating	New	72/100
Pharmacy pays	$0.04 /mL	~$5.35 /30
Type	RX	RX
Active ingredient	IBUPROFEN	PIROXICAM
Manufacturer	Cumberland	Unichem
Dosage forms	Injectable	Capsule
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	Boxed warning
Half-life	about 1.8 to 2.0 hours	—
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	Rheumatoid Arthritis, Inflammation, Osteoarthritis

caldolor piroxicam

Rating

New

72/100

Pharmacy pays

$0.04 /mL

~$5.35 /30

Type

Active ingredient

IBUPROFEN

PIROXICAM

Manufacturer

Cumberland

Unichem

Dosage forms

Injectable

Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 1.8 to 2.0 hours

—

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Rheumatoid Arthritis, Inflammation, Osteoarthritis

Frequently asked questions

What is the difference between Caldolor and Piroxicam?

Caldolor contains Ibuprofen, while Piroxicam contains Piroxicam — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.