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CALDOLOR vs MIDOL LIQUID GELS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 17, 2026·How we rate

Rating

New
70/100

Pharmacy pays

$0.04 /mL
$0.04 /mL

Type

RX
OTC

Active ingredient

IBUPROFEN
IBUPROFEN

Dosage forms

Injectable
Capsule

Drug class

Nonsteroidal Anti-Inflammatory Drug
Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 1.8 to 2.0 hours
about 1.8 to 2.0 hours

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis
Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

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Where to buy

Buy over-the-counter from trusted retailers.

Frequently asked questions

Which is cheaper, Caldolor or Midol Liquid Gels?

Pharmacies pay about the same to acquire either one — roughly $0.04 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Caldolor and Midol Liquid Gels?

Both Caldolor and Midol Liquid Gels share the active ingredient Ibuprofen, but Caldolor is sold as RX and Midol Liquid Gels as OTC.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.