CALDOLOR vs FLECTOR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 15, 2026·How we rate

Possible drug interaction. CALDOLOR and FLECTOR are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CALDOLOR	FLECTOR
Rating	New	72/100
Pharmacy pays	$0.04 /mL	~$146.33 /30
Type	RX	RX
Active ingredient	IBUPROFEN	DICLOFENAC EPOLAMINE
Manufacturer	Cumberland	Ibsa
Dosage forms	Injectable	System
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	Boxed warning
Half-life	about 1.8 to 2.0 hours	about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

caldolor flector

Rating

New

72/100

Pharmacy pays

$0.04 /mL

~$146.33 /30

Type

Active ingredient

IBUPROFEN

DICLOFENAC EPOLAMINE

Manufacturer

Cumberland

Ibsa

Dosage forms

Injectable

System

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

Half-life

about 1.8 to 2.0 hours

about 2 hours (terminal/elimination half-life; the label's table gives a mean of 2.3 hours in healthy adults, with wide variation between people — 48% coefficient of variation)

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Juvenile Arthritis, Rheumatoid Arthritis, Dysmenorrhea

Frequently asked questions

What is the difference between Caldolor and Flector?

Caldolor contains Ibuprofen, while Flector contains Diclofenac Epolamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.