CALDOLOR vs DAYPRO

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 11, 2026·How we rate

Possible drug interaction. CALDOLOR and DAYPRO are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CALDOLOR	DAYPRO
Rating	New	64/100
Pharmacy pays	$0.04 /mL	~$17.64 /30
Type	RX	RX
Active ingredient	IBUPROFEN	OXAPROZIN
Manufacturer	Cumberland	Pfizer
Dosage forms	Injectable	Tablet
Drug class	Nonsteroidal Anti-Inflammatory Drug	Nonsteroidal Anti-Inflammatory Drug
Boxed warning	Boxed warning	None
Half-life	about 1.8 to 2.0 hours	—
Treats	Juvenile Arthritis, Rheumatoid Arthritis, Bursitis	Juvenile Arthritis, Rheumatoid Arthritis, Osteoarthritis

caldolor daypro

Rating

New

64/100

Pharmacy pays

$0.04 /mL

~$17.64 /30

Type

Active ingredient

IBUPROFEN

OXAPROZIN

Manufacturer

Cumberland

Pfizer

Dosage forms

Injectable

Tablet

Drug class

Nonsteroidal Anti-Inflammatory Drug

Boxed warning

None

Half-life

about 1.8 to 2.0 hours

—

Treats

Juvenile Arthritis, Rheumatoid Arthritis, Bursitis

Juvenile Arthritis, Rheumatoid Arthritis, Osteoarthritis

Frequently asked questions

What is the difference between Caldolor and Daypro?

Caldolor contains Ibuprofen, while Daypro contains Oxaprozin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.