CAFERGOT vs MYSOLINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. CAFERGOT and MYSOLINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CAFERGOT	MYSOLINE
Rating	70/100	74/100
Pharmacy pays	~$2.63 /30	~$2.89 /30
Type	RX	RX
Active ingredient	CAFFEINE AND ERGOTAMINE TARTRATE	PRIMIDONE
Manufacturer	Novartis	Valeant Pharm Intl
Dosage forms	Tablet	Tablet
Drug class	—	Anti-Epileptic Agent
Boxed warning	None	None
Treats	—	Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

cafergot mysoline

Rating

70/100

74/100

Pharmacy pays

~$2.63 /30

~$2.89 /30

Type

Active ingredient

CAFFEINE AND ERGOTAMINE TARTRATE

PRIMIDONE

Manufacturer

Novartis

Valeant Pharm Intl

Dosage forms

Tablet

Drug class

—

Anti-Epileptic Agent

Boxed warning

None

Treats

—

Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor

Frequently asked questions

Which is better-rated, Cafergot or Mysoline?

By our independent rating, Mysoline scores higher — 3.7 vs 3.5 out of 5 for Cafergot. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Cafergot or Mysoline?

Cafergot costs pharmacies less to acquire — about $2.63 vs $2.89 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cafergot and Mysoline?

Cafergot contains Caffeine and Ergotamine Tartrate, while Mysoline contains Primidone — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.