CAFERGOT vs CUPRIMINE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 6, 2026·How we rate

Possible drug interaction. CAFERGOT and CUPRIMINE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CAFERGOT	CUPRIMINE
Rating	70/100	74/100
Pharmacy pays	~$2.63 /30	—
Type	RX	RX
Active ingredient	CAFFEINE AND ERGOTAMINE TARTRATE	PENICILLAMINE
Manufacturer	Novartis	Valeant Pharm Intl
Dosage forms	Tablet	Capsule
Drug class	—	Antirheumatic Agent
Boxed warning	None	Boxed warning
Treats	—	Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

cafergot cuprimine

Rating

70/100

74/100

Pharmacy pays

~$2.63 /30

—

Type

Active ingredient

CAFFEINE AND ERGOTAMINE TARTRATE

PENICILLAMINE

Manufacturer

Novartis

Valeant Pharm Intl

Dosage forms

Tablet

Capsule

Drug class

—

Antirheumatic Agent

Boxed warning

None

Boxed warning

Treats

—

Rheumatoid Arthritis, Cystinuria, Hepatolenticular Degeneration

Frequently asked questions

Which is better-rated, Cafergot or Cuprimine?

By our independent rating, Cuprimine scores higher — 3.7 vs 3.5 out of 5 for Cafergot. Ratings are based on FDA regulatory (recall-safety) data.

What is the difference between Cafergot and Cuprimine?

Cafergot contains Caffeine and Ergotamine Tartrate, while Cuprimine contains Penicillamine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.