CAFCIT vs RELEXXII

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Possible drug interaction. CAFCIT and RELEXXII are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	CAFCIT	RELEXXII
Rating	72/100	70/100
Pharmacy pays	~$2.58 /30	~$18.94 /30
Type	RX	RX
Active ingredient	CAFFEINE CITRATE	METHYLPHENIDATE HYDROCHLORIDE
Manufacturer	Hikma	Osmotica Pharm US
Dosage forms	Injectable	Tablet, extended release
Drug class	Central Nervous System Stimulant	Central Nervous System Stimulant
Boxed warning	None	Boxed warning
Half-life	—	about 2.7 hours
Treats	Apnea, Fatigue	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

cafcit relexxii

Rating

72/100

70/100

Pharmacy pays

~$2.58 /30

~$18.94 /30

Type

Active ingredient

CAFFEINE CITRATE

METHYLPHENIDATE HYDROCHLORIDE

Manufacturer

Hikma

Osmotica Pharm US

Dosage forms

Injectable

Tablet, extended release

Drug class

Central Nervous System Stimulant

Boxed warning

None

Boxed warning

Half-life

—

about 2.7 hours

Treats

Apnea, Fatigue

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy

Frequently asked questions

Which is better-rated, Cafcit or Relexxii?

By our independent rating, Cafcit scores higher — 3.6 vs 3.5 out of 5 for Relexxii. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Cafcit or Relexxii?

Cafcit costs pharmacies less to acquire — about $2.58 vs $18.94 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Cafcit and Relexxii?

Cafcit contains Caffeine Citrate, while Relexxii contains Methylphenidate Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.