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BYSTOLIC vs METOPROLOL TARTRATE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Possible drug interaction. BYSTOLIC and METOPROLOL TARTRATE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

70/100
60/100

Pharmacy pays

~$4.06 /30
~$0.58 /30

Type

RX
RX

Active ingredient

NEBIVOLOL HYDROCHLORIDE
METOPROLOL TARTRATE

Manufacturer

Dosage forms

Tablet
Injectable, Solution, Tablet

Drug class

Beta-Adrenergic Blocker
Beta-Adrenergic Blocker

Boxed warning

None
None

Half-life

about 3 to 4 hours

Treats

Malignant Hypertension
Angina Pectoris, Atrial Fibrillation, Atrial Flutter

Frequently asked questions

Which is better-rated, Bystolic or Metoprolol Tartrate?

By our independent rating, Bystolic scores higher — 3.5 vs 3.0 out of 5 for Metoprolol Tartrate. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Bystolic or Metoprolol Tartrate?

Metoprolol Tartrate costs pharmacies less to acquire — about $0.58 vs $4.06 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Bystolic and Metoprolol Tartrate?

Bystolic contains Nebivolol Hydrochloride, while Metoprolol Tartrate contains Metoprolol Tartrate — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.