BUSPIRONE HYDROCHLORIDE vs IMIPRAMINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 13, 2026·How we rate

Possible drug interaction. BUSPIRONE HYDROCHLORIDE and IMIPRAMINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BUSPIRONE HYDROCHLORIDE	IMIPRAMINE HYDROCHLORIDE
Rating	70/100	70/100
Pharmacy pays	~$1.27 /30	~$2.54 /30
Type	RX	RX
Active ingredient	BUSPIRONE HYDROCHLORIDE	IMIPRAMINE HYDROCHLORIDE
Manufacturer	Impax	Strides Pharma Intl
Dosage forms	Tablet	Tablet
Drug class	—	Tricyclic Antidepressant
Boxed warning	None	Boxed warning
Half-life	about 2 to 3 hours	—
Treats	Anxiety Disorders, Depressive Disorder, Intellectual Disability	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

buspirone hydrochloride imipramine hydrochloride

Rating

70/100

Pharmacy pays

~$1.27 /30

~$2.54 /30

Type

Active ingredient

BUSPIRONE HYDROCHLORIDE

IMIPRAMINE HYDROCHLORIDE

Manufacturer

Impax

Strides Pharma Intl

Dosage forms

Tablet

Drug class

—

Tricyclic Antidepressant

Boxed warning

None

Boxed warning

Half-life

about 2 to 3 hours

—

Treats

Anxiety Disorders, Depressive Disorder, Intellectual Disability

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

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Frequently asked questions

Which is better-rated, Buspirone Hydrochloride or Imipramine Hydrochloride?

Buspirone Hydrochloride and Imipramine Hydrochloride are tied at 3.5 out of 5 by our independent rating.

Which is cheaper, Buspirone Hydrochloride or Imipramine Hydrochloride?

Buspirone Hydrochloride costs pharmacies less to acquire — about $1.27 vs $2.54 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Buspirone Hydrochloride and Imipramine Hydrochloride?

Buspirone Hydrochloride contains Buspirone Hydrochloride, while Imipramine Hydrochloride contains Imipramine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.