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BUPRENORPHINE HYDROCHLORIDE vs DOLOBID

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 12, 2026·How we rate

Possible drug interaction. BUPRENORPHINE HYDROCHLORIDE and DOLOBID are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
70/100

Pharmacy pays

~$683.94 /30
~$34.89 /30

Type

RX
RX

Active ingredient

BUPRENORPHINE HYDROCHLORIDE
DIFLUNISAL

Manufacturer

Dosage forms

Injectable, Solution, Tablet
Tablet

Drug class

Partial Opioid Agonist

Boxed warning

None
None

Treats

Heroin Dependence, Pain
Rheumatoid Arthritis, Osteoarthritis, Pain

Frequently asked questions

Which is better-rated, Buprenorphine Hydrochloride or Dolobid?

By our independent rating, Buprenorphine Hydrochloride scores higher — 3.6 vs 3.5 out of 5 for Dolobid. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Buprenorphine Hydrochloride or Dolobid?

Dolobid costs pharmacies less to acquire — about $34.89 vs $683.94 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Buprenorphine Hydrochloride and Dolobid?

Buprenorphine Hydrochloride contains Buprenorphine Hydrochloride, while Dolobid contains Diflunisal — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.