BRYNOVIN vs FORTAMET

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate

Possible drug interaction. BRYNOVIN and FORTAMET are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BRYNOVIN	FORTAMET
Rating	72/100	New
Pharmacy pays	~$110.51 /30	~$0.74 /30
Type	RX	RX
Active ingredient	SITAGLIPTIN HYDROCHLORIDE	METFORMIN HYDROCHLORIDE
Manufacturer	Azurity	Andrx Labs LLC
Dosage forms	Solution	Tablet, extended release
Drug class	Dipeptidyl Peptidase 4 Inhibitor	Biguanide
Boxed warning	None	None
Half-life	about 12.4 hours (apparent terminal half-life after a single 100 mg oral dose in healthy volunteers)	about 6.2 hours (plasma elimination half-life in adults with normal kidney function)
Treats	Type 2 Diabetes Mellitus	Type 2 Diabetes Mellitus

brynovin fortamet

Rating

72/100

New

Pharmacy pays

~$110.51 /30

~$0.74 /30

Type

Active ingredient

SITAGLIPTIN HYDROCHLORIDE

METFORMIN HYDROCHLORIDE

Manufacturer

Azurity

Andrx Labs LLC

Dosage forms

Solution

Tablet, extended release

Drug class

Dipeptidyl Peptidase 4 Inhibitor

Biguanide

Boxed warning

None

Half-life

about 12.4 hours (apparent terminal half-life after a single 100 mg oral dose in healthy volunteers)

about 6.2 hours (plasma elimination half-life in adults with normal kidney function)

Treats

Type 2 Diabetes Mellitus

Get brynovinhigher-rated option

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Frequently asked questions

Which is cheaper, Brynovin or Fortamet?

Fortamet costs pharmacies less to acquire — about $0.74 vs $110.51 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Brynovin and Fortamet?

Brynovin contains Sitagliptin Hydrochloride, while Fortamet contains Metformin Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.