BRISDELLE vs PAROXETINE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. BRISDELLE and PAROXETINE HYDROCHLORIDE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BRISDELLE	PAROXETINE HYDROCHLORIDE
Rating	New	66/100
Pharmacy pays	~$2.84 /30	~$2.84 /30
Type	RX	RX
Active ingredient	PAROXETINE MESYLATE	PAROXETINE HYDROCHLORIDE
Manufacturer	Legacy Pharma	Apotex
Dosage forms	Capsule	Suspension, Tablet, extended release
Drug class	Serotonin Reuptake Inhibitor	Serotonin Reuptake Inhibitor
Boxed warning	Boxed warning	None
Half-life	about 21 hours on average (the label reports a mean of approximately 21 hours, with 32% variability between people)	about 21 hours on average (the label reports a mean of approximately 21 hours, with 32% variability between people)
Treats	Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder	Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

brisdelle paroxetine hydrochloride

Rating

New

66/100

Pharmacy pays

~$2.84 /30

Type

Active ingredient

PAROXETINE MESYLATE

PAROXETINE HYDROCHLORIDE

Manufacturer

Legacy Pharma

Apotex

Dosage forms

Capsule

Suspension, Tablet, extended release

Drug class

Serotonin Reuptake Inhibitor

Boxed warning

None

Half-life

about 21 hours on average (the label reports a mean of approximately 21 hours, with 32% variability between people)

Treats

Feeding and Eating Disorders, Depressive Disorder, Obsessive-Compulsive Disorder

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Frequently asked questions

Which is cheaper, Brisdelle or Paroxetine Hydrochloride?

Pharmacies pay about the same to acquire either one — roughly $2.84 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Brisdelle and Paroxetine Hydrochloride?

Brisdelle contains Paroxetine Mesylate, while Paroxetine Hydrochloride contains Paroxetine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.